Description
Carboxyl-activated SepFast MAG is used to make magnetic chromatography adsorbents.
The base matrix is activated by attaching a long 10 atom hydrophilic chain with a carboxyl group at the end. This reacts with amine containing ligands in the presence of carbodiimide agent to form a chemically stable amide linkage. The coupling chemistry is a successful and well-documented technique.
Carboxyl-activated SepFast MAG 4 High Flow (4HF) is made of highly cross-linked 4% agarose with magnetic properties.
Agarose has long been used for chromatographic separations due to its excellent hydrophilic and low non-specific-binding nature. The particles have an open pore structure with excellent mass transfer properties to large protein molecules.
The pre-activated base matrix can be readily employed to make various magnetic chromatography adsorbents for a variety of purification applications. After binding of target molecules, the magnetic resin can be readily isolated from the biological feedstocks with the aid of a magnet.
Coupling manual is supplied with each product.